The Clinically
Studied Ingredient
Behind Every Chew
Sharp Brain Chews are powered by Cognizin® Citicoline—16+ years of clinical research in a delicious daily chew that supports memory, focus, mental energy, and processing speed.*
Shop Sharp Brain
30-Day Money Back Guarantee
Clinically-Researched Cognizin®
Delicious Soft Chews Caramel apple flavor
Caffeine-Free No jitters, no crash
Only 2g Sugar Clean ingredients
Pill-Free Formula Easy daily routine
Clinically-Researched Cognizin®
Delicious Soft Chews Caramel apple flavor
Caffeine-Free No jitters, no crash
Only 2g Sugar Clean ingredients
Pill-Free Formula Easy daily routine
Meet Your Brain’s
Favorite Nutrient
Meet Your Brain’s
Favorite Nutrient
Cognizin® is a patented, clinically studied form of citicoline—a naturally occurring compound found in every cell of your body and especially vital to brain health. Your brain makes up only 2% of your body weight, yet it consumes 20% of your energy. Cognizin® helps fuel that demand.*
Unlike generic citicoline supplements, Cognizin® is produced through a proprietary fermentation process that ensures purity, bioavailability, and consistency—batch after batch. It’s the only form of citicoline studied specifically in healthy adults, with over 16 years of published clinical research backing its benefits.*
Every serving of Sharp Brain Chews delivers 250 mg of Cognizin® Citicoline—the same clinically studied dose shown to support focus, attention, accuracy, and productivity.*
Patented & Clinically Studied
Allergen-Free & Vegetarian
GRAS - Generally Recognized as Safe
Three Ways
Cognizin®
Supports Your Brain
Your brain is the most energy-hungry organ in your body.
Cognizin® works through three distinct mechanisms to keep it firing on all cylinders.*
Your brain is the most energy-hungry organ in your body. Cognizin® works through three distinct mechanisms to keep it firing on all cylinders.*
Powers your
brain’s energy supply
Cognizin® supports the production of ATP—your brain’s primary energy source. In clinical research, Cognizin® supplementation supported brain energy utilization, helping fuel the mental energy you need to think clearly and stay sharp throughout the day.*
Builds & Protects
Brain Cells
Cognizin® provides the building blocks for phosphatidylcholine—a critical phospholipid that makes up your brain cell membranes. Healthy membranes mean better communication between neurons, stronger cell signaling, and long-term structural support for your brain.*
Supports key
neurotransmitters
Cognizin® supports healthy levels of acetylcholine—the neurotransmitter essential for memory, learning, and attention. It also supports dopamine and norepinephrine levels, which play roles in motivation, mood, and mental clarity.*
Science
You Can Trust
Cognizin® isn’t just another supplement ingredient—it’s one of the most researched branded forms of citicoline available. Here’s what the published science says.*
16+
Years of Clinical Research
14%
Increase in BrainEnergy (ATP)*
26%
Increase in Brain Cell
Membrane Formation*
Key Published Studies
Brain Energy
& Membrane Synthesis
Silveri et al., 2008 — NMR in Biomedicine
Population: Healthy adults aged 40–60
Dose: 500 mg/day for 6 weeks
Key Finding:
Participants who supplemented with Cognizin® at 500 mg/day showed a 14% increase in brain ATP levels and a 26% increase in phospholipid membrane formation in the frontal lobe—regions critical for focus, decision-making, and mental clarity.*
Attention & Focus
in Healthy Women
McGlade et al., 2012 — Food and Nutrition Sciences
Population: Healthy women aged 40–60
Dose: 250 mg/day for 28 days
Key Finding:
Women taking Cognizin® at 250 mg/day showed improved attentional performance and reduced errors on cognitive tasks, suggesting better focus and accuracy under real-world
conditions.*
Motor Speed & Attention
in Adolescent Males
McGlade et al., 2019 — Journal of Attention Disorders
Population: Adolescent males
Dose: 250 mg/day for 28 days
Key Finding:
Participants demonstrated improvements in attention, motor speed, and processing accuracy—supporting Cognizin®’s role in psychomotor performance and the ability to process and react to information faster.*
Memory in Healthy
Older Adults
Nakazaki et al., 2021 — The Journal of Nutrition
Population: Healthy adults aged 50–85
Dose: 500 mg/day for 12 weeks
Key Finding:
Older adults supplementing with Cognizin® showed significant improvements in episodic memory and overall memory performance as measured by the Creyos (Cambridge Brain Sciences) cognitive assessment platform.*
Cognitive Health
& Antioxidant Support
Al-Kuraishy et al., 2020 — Basic and Clinical Neuroscience
Population: Adult participants
Dose: 250 mg/day
Key Finding:
Cognizin® demonstrated support for cognitive function, motor speed, and processing speed, along with healthy antioxidant activity—helping the body reduce oxidative stress that can affect long-term brain health.*
References:
Silveri MM et al. NMR Biomed. Nov 2008;21(10):1066–75.
McGlade E et al. Food and Nutrition Sciences. 2012;03.
McGlade E et al. J Atten Disord. Jan 2019;23(2):121–134.
Nakazaki E et al. J Nutr. Aug 2021;151(8):2153–2160.
Al-Kuraishy HM et al. Basic Clin Neurosci. Jul-Aug 2020;11(4):423–432.
Wurtman RJ et al. Biochem Pharmacol. Oct 2000;60(7):989–92.
Spiers PA et al. Arch Neurol. May 1996;53(5):441–8.
Cotroneo AM et al. Clin Interv Aging. 2013;8:131–7.
Babb SM et al. Psychopharmacology (Berl). May 2002;161(3):248–54.
Knott V et al. Pharmacol Biochem Behav. Apr 2015;131:119–29.
Brain Energy
& Membrane Synthesis
+
Silveri et al., 2008 — NMR in Biomedicine
Population: Healthy adults aged 40–60
Dose: 500 mg/day for 6 weeks
Key Finding:
Participants who supplemented with Cognizin® at 500 mg/day showed a 14% increase in brain ATP levels and a 26% increase in phospholipid membrane formation in the frontal lobe—regions critical for focus, decision-making, and mental clarity.*
Attention & Focus
in Healthy Women
+
McGlade et al., 2012 — Food and Nutrition Sciences
Population: Healthy women aged 40–60
Dose: 250 mg/day for 28 days
Key Finding:
Women taking Cognizin® at 250 mg/day showed improved attentional performance and reduced errors on cognitive tasks, suggesting better focus and accuracy under real-world conditions.*
Motor Speed & Attention
in Adolescent Males
+
McGlade et al., 2019 — Journal of Attention Disorders
Population: Adolescent males
Dose: 250 mg/day for 28 days
Key Finding:
Participants demonstrated improvements in attention, motor speed, and processing accuracy—supporting Cognizin®’s role in psychomotor performance and the ability to process and react to information faster.*
Memory in Healthy
Older Adults
+
Nakazaki et al., 2021 — The Journal of Nutrition
Population: Healthy adults aged 50–85
Dose: 500 mg/day for 12 weeks
Key Finding:
Older adults supplementing with Cognizin® showed significant improvements in episodic memory and overall memory performance as measured by the Creyos (Cambridge Brain Sciences) cognitive assessment platform.*
Cognitive Health
& Antioxidant Support
+
Al-Kuraishy et al., 2020 — Basic and Clinical Neuroscience
Population: Adult participants
Dose: 250 mg/day
Key Finding:
Cognizin® demonstrated support for cognitive function, motor speed, and processing speed, along with healthy antioxidant activity—helping the body reduce oxidative stress that can affect long-term brain health.*
References:
Silveri MM et al. NMRBiomed.Nov2008;21(10):1066–75.McGlade E et al. Food and Nutrition Sciences. 2012;03. McGlade E et al. J Atten Disord. Jan 2019;23(2):121–134.Nakazaki E et al. J Nutr. Aug 2021;151(8):2153–2160.Al-Kuraishy HM et al. Basic Clin Neurosci. Jul-Aug 2020;11(4):423–432.
Wurtman RJ et al. Biochem Pharmacol. Oct 2000;60(7):989–92.
Spiers PA et al. Arch Neurol. May 1996;53(5):441–8.
Cotroneo AM et al. Clin Interv Aging. 2013;8:131–7.
Babb SM et al. Psychopharmacology (Berl). May 2002;161(3):248–54.
Knott V et al. Pharmacol Biochem Behav. Apr 2015;131:119–29.
Clinically Studied.
Deliciously Delivered.
We didn’t just pick any citicoline for Sharp Brain Chews. We chose Cognizin® because it’s the gold standard—patented, rigorously tested in healthy adults, and backed by the kind of clinical evidence that most brain health supplements can only put on a wish list.*
Most cognitive health supplements come in hard-to-swallow pills and rely on generic, untested ingredients. Sharp Brain is different. Every chew delivers 250 mg of Cognizin® Citicoline in a delicious caramel apple soft chew—no pills, no capsules, no chalky tablets. Just a treat that’s actually good for your brain.*
Try Sharp Brain Chews Today
Subscribe & Save up to 10%
250 mg Cognizin® Citicoline per serving the clinically studied daily dose for focus, attention, and accuracy*
500 mg Organic Lion’s Mane Mushroom Extract a traditional nootropic for long-term brain health support*
Essential B-Vitamins (B3, B9, B12) to support cellular energy production and healthy brain function*
Caffeine-free, gluten-free, vegetarian, no artificial colors or flavors
Only 2g sugar per serving delicious caramel apple flavor
Individually wrapped soft chews easy to take anywhere,share with anyone 18+
A Smarter Formula,
Working Together
Combining citicoline with lion’s mane mushroom and B vitamins (vitamin B3, vitamin B9, vitamin B12) supportsbrain health across key pathways—neurotransmitter function, neural repair,and cellular energy —providing comprehensive support for memory, concentration, and cognitive performance.
INGREDIENT
Per Serving
How It Supports Your Brain*
Cognizin®
Citicoline
250 mg
Cognizin®
Citicoline
250 mg
Supports focus, attention, accuracy, mental energy, and brain cell membrane formation. The clinically studied backbone of the Sharp Brain formula.*
Organic Lion’s Mane
Mushroom Extract
500 mg
Organic Lion’s Mane
Mushroom Extract
250 mg
A revered nootropic mushroom traditionally used to support long-term brain health, cognitive function, and nerve cell growth.*
B-Vitamins
(B3, B9, B12)
250 mcg
B-Vitamins (B3, B9, B12)
250 mcg
Essential cofactors that support cellular energy production, healthy neurotransmitter synthesis, and overall brain function.*
Frequently Asked
Questions
No matter what your question is or concerns, we have all of them.
If you have any questions that aren't answered below, email us at
No matter what your question is or concerns, we have all of them.If you have any questions that aren't answered below, email us at
What is Cognizin® Citicoline?
Cognizin® is a patented, clinically studied form of citicoline—a naturally occurring compound that plays a vital role in brain health. It’s produced through a proprietary fermentation process and is the only form of citicoline studied specifically in healthy adults. Each serving of Sharp Brain Chews delivers 250 mg of Cognizin®.*
How is citicoline different from regular choline?
While both are related, citicoline (CDP-choline) is a more complete compound. When you take citicoline, your body breaks it down into choline and cytidine. The choline supports acetylcholine production for memory and learning, while cytidine converts to uridine—which supports the structural integrity of brain cell membranes. Think of citicoline as a two-in-one delivery system for brain nutrition.*
Why 250 mg? Is that enough?
Yes. Multiple clinical studies have demonstrated meaningful cognitive benefits at 250 mg/day of Cognizin®, including improvements in focus, attention, and accuracy. This is the dose used in key published studies. Some studies also use 500 mg/day and show additional benefits for memory and brain energy. Sharp Brain’s formula pairs 250 mg of Cognizin® with complementary ingredients like Lion’s Mane for comprehensive support.*
How long before I notice results?
Some people report feeling sharper within the first few weeks, but the clinical research shows the most significant benefits emerge with consistent daily use over 4–12 weeks. Brain health is a long game—Cognizin® is designed to support your brain over time, not deliver an instant jolt like caffeine.*
Is Cognizin® safe?
Cognizin® has achieved GRAS (Generally Recognized as Safe) status and has been studied in multiple clinical trials with healthy adults. Sharp Brain Chews are caffeine-free, gluten-free, vegetarian, and contain no artificial colors or flavors. As with any supplement, consult a healthcare professional before use if you are pregnant, nursing, taking medication, or have a medical condition.
Why chews instead of pills?
Because compliance matters. The best supplement in the world doesn’t work if it stays in the bottle. Sharp Brain Chews are formulated as delicious caramel apple soft chews so you’ll actually look forward to taking them every day. No water needed, no swallowing large capsules—just a tasty daily habit for your brain.*
Can I take Sharp Brain Chews with other supplements?
Sharp Brain Chews are formulated with well-researched, non-stimulant ingredients. However, we always recommend discussing your supplement routine with a healthcare professional, especially if you take prescription medications.
Feed Your Brain.
Skip the Pills.
Feed Your Brain.
Skip the Pills.
Sharp Brain Chews deliver clinically studied Cognizin® Citicoline, Organic Lion’s Mane, and essential B-Vitamins in a delicious caramel apple soft chew. Take two a day—one in the morning, one in the afternoon—and give your brain the daily support it deserves.*
